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Main Street Inn B&B

221 North Main Street , Sainte Genevieve, MO 63670 USA (Show map)
9 Reviews
$98 - $150
per night

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Main Street Inn has spacious, quietly elegant, unpretentious accommodations that even husbands find comfortable - no clutter and no country-cute. Built in the 1880s in the heart of historic French colonial Ste. Genevieve - Missouri's oldest town, It has been exquisitely restored. Its bright, spacious parlors, dining room (with grand piano), porches, and garden beckon visitors to stay awhile and relax. Traditional and antique furniture combine with vintage linens creating comfortable rooms with modern conveniences and state-of-the-art heating & cooling. All private baths with showers; three large whirlpool suites, one with fireplace.



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  • Guest room4.8
  • Services4.9
  • Value4.6
  • Cleanliness4.9
  • Dining4.9

Score Breakdown based on
9 Reviews

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Very, very nice

4.4 on June 30, 2014

Kay graciously switched our room when my husband wanted a TV in the room. The breakfast was great. The antique decor was wonderful. The whole experience was great. I want to return again.

Great weekend!

5 on December 21, 2013

A wonderful hidden gem. Relaxing, quiet, the proprietors are attentive to every detail.

Clean and cozy

5 on January 19, 2011

This place is quiet and unbelieveably clean. Bed was comfortable and the bedding was crisp with weighty cozy!! I found it charming and in a great location. Hosts were hospitable and helpful and at the same time respected our privacy. We loved breakfast. I might suggest a little classical music to add to the charm, I love a mood setter :) If you want charming, cozy and super super clean..this is the place and we will return! Jim & Mindy

Main Street B&B

4.8 on November 07, 2010

Very flexible in adjusting reservations. Large, comfortable rooms. Great breakfast. Innkeepers were friendly and very accomodating.

foodie's dream!

5 on August 20, 2010

Me and my husband stayed the night and had a wonderful experience. Great place for a foodie like me! Breakfast was wonderful and decadant. We enjoyed the hospitality immensely. The owners that evening pointed us in the direction of some great local restaurants. Only thing of the trip I would take back, is taking advice from the visitor center in town.They pointed us to lunch at the Brick House before checking in, food was so blah and disapointing. Our hosts at the B&B mentioned that evening right across the street is a wonderful lunch cafe' with a mouthwatering menu. Take their advice on restaurants- I so wish we would have known to ask.

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Location Type

National Historic District, Countryside, Small town, Village


St. Louis, MO (STL-Lambert-St. Louis Intl.) 80 miles

Area Attractions

Art Galleries, Gourmet/Fine Dining, Museum, Nature area

Inn Details

Establishment type

Bed and Breakfast, Historic Inn

On-site amenities

Board games, Conference Rooms, Desk, Fax Machine, Library, Piano, Telephone, Videos

Room amenities

Air conditioning, Alarm clock, Amenities Basket, Ceiling fans, In-room internet, Fireplace, Hot tub/whirlpool tub, Radio, Satellite/Cable TV, VCR, Wi-Fi

On-site activities

Bicycle riding trails, Bird watching, Boating, Golfing, Hiking trails, Wine Tasting, Historic Home Tours, Shopping, Sight-seeing, Swimming pool, Tennis courts

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  • Check In:: After 4:00 pm
  • Check Out:: Noon
  • Open All Year Round: Yes
  • Smoking Allowed: Limited
  • Drinking Allowed: Yes
  • Suitable For Children: Age 12 and above
  • Guest Pets Allowed: No

Terms and Conditions

  • Minimum Stay: Two nights on holiday weekends & during special events
  • Deposit Amount Required: Reservations are guaranteed by credit card authorization or receipt of a check for the first night's stay.
  • Cancellations: Deposits are refundable with up to seven days advance notice of cancellation. Late arrivals should be arranged in advance.



Kay Cook

Languages spoken


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  • Time Served: 9 - 10 am
  • Serving Location: Dining Room

Special meal options

Low fat , Restrictive , Vegetarian , special diet-request

Signature Dish

Apricot filled French Toast with Caramel Pecans
Amazingly light version of a decadent French Toast. Garnished with seasonal fresh fruit and herbs and served with locally-smoked baked sausage.

Details Diamond Collection

221 North Main Street , Sainte Genevieve, MO 63670 USA (Show map)

Property highlights

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